Changes to Medi-Cal Rx – 60-day Countdown


Date: November 05, 2025
From: Health Plan of San Joaquin/Mountain Valley Health Plan (“Health Plan”)
To: Health Plan Practitioners, Facilities, and Hospitals
Type: Informational/Educational
Subject: Changes to Medi-Cal Rx – 60-day Countdown
Business: Medi-Cal Managed Care

Medi-Cal Rx Pharmacy Benefit Changes for all Medi-Cal Members.

Effective January 1, 2026, the following changes will be implemented to the Medi-Cal Rx Coverage Policies.

GLP-1 Drugs

  • GLP-1 drugs for the use of weight loss related indications will no longer be covered by Medi-Cal Rx.
  • Medi-Cal Rx will continue to cover GLP-1 drugs for members with type 2 diabetes or other non-weight loss indicated diagnosis only.
  • Letters were mailed in October 2025 informing the members of the change.

Over the Counter (OTC) COVID-19 Antigen Tests

  • Prior authorization (PA) will be required for the dispensing of OTC COVID-19 antigen tests.
  • PA submissions must include the following information:
    1. ICD-10 code.
    2. Signs and symptoms.
    3. Date of most recent COVID -19 test taken.
    4. Documentation of medical necessity.
  • If PA is approved, allowance is a one-time fill of up to 4 tests per month.

Excludes any prescribed by a California Children Services (CCS) Paneled Provider, for members ages 21 and under – refer to https://medi-calrx.dhcs.ca.gov/cms/medicalrx/static-assets/documents/provider/publications/2025.01_A_CCS_Panel_Authority_Policy_Exclusions.pdf.

  • Additional information regarding this coverage will be provided by Medi-Cal Rx after January 1, 2026.

Continuing Care

  • PA will be required for drugs that are currently covered as continuation of care exceptions. Use of alternate covered drugs may be required prior to approval of the non-covered drugs.
  • Impacted drugs:
    • Chlorpromazine 25 mg/ml and 50 mg/2 ml ampules and vials
    • Fluphenazine 2.5 mg/ml vial
    • Haloperidol deconate 50 mg/ml and 100 mg/ml ampules
    • Haloperidol lactate 5 mg/ml ampules, vials, and syringes
    • Timolol 0.25% and 0.5% gel-solution
    • Timolol maleate 0.25% and 0.5% eye solution
    • Bimatoprost 0.03% eye drops
    • Adhansia XR (methylphenidate) 25 mg, 35 mg, 45 mg, 55 mg, 70 mg, and 85 mg capsules
  • Letters were mailed in October 2025 informing the affected members of the change.

Coverage Policies for Select OTC Products

  • Select OTC products, the coverage policies apply to members 21 years of age and older only. Excludes any prescribed by a CCS Paneled Provider. Refer to CCS Panel Authority Policy Exclusions List for covered drugs/products.

Updated drug coverage:

    • Multivitamins combination products will no longer be covered.
    • Certain single-ingredient vitamins and dry eye products will require PA with medical necessity reasons.
    • Restriction of 1st and 2nd generation antihistamines to generic formulations.
    • Restriction of single ingredient vitamin and antihistamines to 90 to 100 days’ supply per fill.
  • OTC prenatal vitamins, limited to use during pregnancy or lactation conditions for members between ages 10 and 60 only. Restriction of 90 to 100 days’ supply for maintenance fills. First fill will be approved for only a 30-day supply to ensure medication tolerance.

Step Therapy

  • Medi-Cal Rx prefers use of drugs/products listed in the “Contract Drugs List” and “Covered Products List” prior to considering approval of non-covered drugs/products. Located on the following website: https://medi-calrx.dhcs.ca.gov/home/cdl/
    • Consider first covered therapies that don’t require a PA.
    • If covered drug/product isn’t clinically appropriate, submit PA to establish medical necessity.
    • Must include tried and considered drugs/products with reason of failure on the PA submission.
    • Continuation of therapy will not suffice as justification for approval.
    • This change applies to ALL members.

Additional details and resources can be found via the Medi-Cal Rx links below:
https://medi-calrx.dhcs.ca.gov/cms/medicalrx/static-assets/documents/provider/2025/11_A_60-Day_Upcoming_Changes_Medi-Cal_Rx.pdf


If you have any further questions, please contact your Provider Services Representative, or call our Customer Service Department at 1-888-936-PLAN (7526). You may also visit https://www.hpsj.com/alerts/ for online access to the documents shared. The most recent information about Health Plan and our services is always available on our website www.hpsj-mvhp.org

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Posted on November 5th, 2025 and last modified on November 5th, 2025.

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